a 中国科学院煤制乙二醇及相关技术重点实验室 结构化学国家重点实验室 中国科学院福建物质结构研究所 福州 350002;
b 洛阳师范学院化学化工学院 471022
Pd/MgO：A Recyclable, Ligand-free Heterogeneous Catalyst for Decarboxylative Cross-Coupling of Arene Carboxylic Acids with Aryl Halides
Li Zhaohaob, Chen Jinga, Su Weipinga, Hong Maochuna
a Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002;
b College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022
Decarboxylative coupling of arene carboxylic acids with aryl halides is achieved by using a ligand-free Pd/MgO (0.5 mol% Pd) heterogeneous catalyst system. Both electron-rich and electron-deficient arene carboxylic acids can be used as aryl sources to couple a variety of aryl bromides, even aryl chlorides in moderate-to-excellent yields. The establishment of heterogeneous catalysis for the decarboxylative cross-coupling along with the reusability of the heterogeneous catalyst should facilitate the practical application of this transformation in organic synthesis.